2020-12-15 OMA Agenda - Board of Trustees

Table 3. Illustrative Cardiovascular Disease Risk Factors to Consider When Managing Patients with Obesity* (11) Major ASCVD Events • Recent acute coronary syndrome (ACS within the past 12 months) • History of myocardial infarction (other than recent ACS event listed above) • History of stroke • Symptomatic peripheral arterial disease (history of claudication with ABI <0.85, or previous revascularization or amputation High-Risk Conditions

Age ≥65 y

• •

Heterozygous familial hypercholesterolemia

• History of prior coronary artery bypass surgery or percutaneous coronary intervention • Diabetes mellitus • Uncontrolled hypertension • Chronic Kidney Disease • Current smoking • Persistently elevated low-density lipoprotein cholesterol • History of congestive heart failure Risk-Enhancing Factors

• Family history of premature atherosclerotic cardiovascular disease (men, age <55 y; women, age <65 y) • Primary hypercholesterolemia • Metabolic syndrome • Chronic kidney disease • Chronic inflammatory conditions (e.g., psoriasis, rheumatoid arthritis, human immunodeficiency virus infection (HIV/AIDS) • Premature menopause (before age 40 y) • Pre-eclampsia • High risk populations (i.e., South Asians) • Persistently elevated triglyceride levels • Elevated high-sensitivity C- reactive protein (≥2.0 mg/L) • Elevated Lipoprotein(a) ( Lp(a) ≥50 mg/dL or ≥125 nmol/L ) • Elevated apolipoprotein B ≥130 mg/dL • Ankle brachial index <0.9

* Not an all-inclusive list

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